![]() Malignant breast lesions were 27.15% of all breast lesions. Other major lesions encountered were, benign phyllodes (a leaf-like growth pattern of stroma), fibrocystic disease of breast (fibrosis, cyst formation), sclerosing adenosis (increased number of distorted lobules, associated with stromal fibrosis), granulomatous mastitis (composed of non-caseating granulomas, giant cells, and foamy histiocytes) and duct ectasia (dilated duct and lymphoplasmacytic infiltrate). Most common benign breast disease of breast was fibroadenoma (45.71%) (Most common histologic change is that of intracanalicular pattern), followed by lactating adenoma (histologic change related to the stage of pregnancy). Eight cases (42.10%) were below the age of 40 years, with an age range of 20-80 years. The mean age for benign diseases of breast was 22.5 years and the age range 10 – 50 years and 19 were malignant lesions. Results: During four and a half year study period, out of 70 cases, 51 were benign lesions (constituting 72.85%of total breast lesions). Detailed gross and microscopic examination was done for each specimen. Samples were received from KBN Hospital Gulbarga, to department of Pathology KBNIMS Gulbarga. The specimens were received in different forms such as excision biopsies, modified radical mastectomies and simple mastectomies. Materials and Method: The present study includes 70 cases from January 2012 to June 2016. Male breast lesions are relatively rare accounting for only 2.3% of all breast lesions in this study.Īims and Objectives: 1) To study the prevalence of breast diseases, and 2) To study the histological patterns in inflammatory breast diseases, benign and malignant lesions of breast. Overall the most affected cohort is the 20 to 29 age group. The predominant conditions diagnosed were fibrocystic changes, invasive ductal carcinoma and fibroadenoma in that order of frequency together constituting 81.6% of the total breast lesions. The major categories of breast diseases seen were inflammatory, tumour-like, benign and malignant tumours. Breast lesions were found to constitute a significant percentage (11.6%) of the total diseases encountered in the department. The main focus of this work is to provide data on breast diseases from a hitherto unexplored centre in the country. In this retrospective study carried out in the National Hospital Abuja the entire specimen received in the department of histopathology over a five year period was reviewed. The histopathologist’s contributions include accurate and timely diagnosis of breast masses and highlighting linkages between morphologic appearances and clinical behaviour of these diseases. Efforts to arrest this global scourge involve contributions from clinicians, radiologists, oncologists, radiotherapists, surgeons, pathologists as well as intense clinical studies and researches. Women, who have been diagnosed as having proliferative breast disease, require careful follow-up, with annual mammographic screening being mandatory for women with atypical hyperplasia.īreast diseases are significant cause of morbidity and mortality worldwide posing a serious challenge to patients, clinicians, and pathologists. ![]() Conclusion: Proliferative lesions in the breast carry an increased risk of developing malignancies especially when there is atypia. Of 38 cases, proliferative lesions with atypia were noted in 20 cases and proliferative lesions without atypia were noted in 18 cases. ![]() Proliferative breast lesions were noted in 38 cases (38%), nonproliferative breast lesions in 27 cases (27%) and there were no changes in 35 cases (35%). The predominant type of carcinoma (85%) was infiltrating ductal carcinoma-no specific type. ![]() Results: The study included 100 cases of breast carcinomas. The tumor and the surrounding breast tissue were studied grossly and microscopically for any co-existing neoplastic and non neoplastic lesions like epithelial hyperplasia, cystic change, apocrine metaplasia, fibrosis and adenosis. Material and methods: The present study included 100 cases of mastectomies for carcinoma breast at Kempegowda Institute of Medical Sciences, Bangalore from August 2010 to July 2013. The study was undertaken to know the frequency of proliferative fibrocystic lesions in association with breast carcinomas in mastectomy specimens. Proliferative breast diseases are recognized as one of the risk factors in the development of carcinoma. Background: Breast cancer remains a global health problem with an increasing incidence.
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